Maternal serum alpha-fetoprotein levels in multiple pregnancy.

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چکیده

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Maternal Serum Alpha-Fetoprotein Screening

Background: The maternal serum alpha-fetoprotein test (MSAFP) was developed to screen for neural tube defects. Little is known about the adoption of the MSAFP test. This study examines the effect of provider specialty and geographic location and patient insurance status on MSAFP test use in Washington State. Methods: We conducted a retrospective cohort study of MSAFP use in low-risk obstetric p...

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Serum alpha-fetoprotein in the three trimesters of pregnancy: effects of maternal characteristics and medical history.

OBJECTIVE To define the contribution of maternal variables which influence the measured level of maternal serum alpha-fetoprotein (AFP) in screening for pregnancy complications. METHODS Maternal characteristics and medical history were recorded and serum AFP was measured in women with a singleton pregnancy attending for three routine hospital visits at 11 + 0 to 13 + 6, 19 + 0 to 24 + 6 and 3...

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Maternal serum alpha-fetoprotein in normal pregnancy at 11-13 weeks' gestation.

OBJECTIVE To establish a reference distribution of maternal serum alpha-fetoprotein (AFP) at 11-13 weeks' gestation and define the contribution of maternal variables that influence the measured concentration of AFP. METHODS Serum concentration of AFP at 11-13 weeks was measured in 1,500 singleton pregnancies which were not complicated by hypertensive disorders or diabetes mellitus and resulte...

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Effects of alcohol, cigarettes, methamphetamine and marijuana exposure during pregnancy on maternal serum alpha-fetoprotein levels at 20-24 weeks’gestation

Addressing the burden of stillbirths is a worldwide priority.1 As many stillbirths are not associated with known risk factors, including previous obstetric history in primigravidas,2 the value of routine blood tests such as maternal serum alpha-fetoprotein (MSAFP) to identify pregnant women at risk should be explored. Although the main indication for MSAFP analyses in the mid-trimester is the e...

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ژورنال

عنوان ژورنال: BMJ

سال: 1975

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.1.5959.651